Territory size depends largely on the amount of prey available and the age of the pack's pups, tending to increase in size in areas with low prey populations  or when the pups reach the age of 6 months, thus having the same nutritional needs as adults. The AAS, whether of endogenous or exogenous origin, are subject to extensive hepatic biotransformation by a variety of enzymatic pathways. Some examples of the anabolic effects of these hormones are increased protein synthesis from amino acids , increased appetite, increased bone remodeling and growth, and stimulation of bone marrow , which increases the production of red blood cells. Archived from the original on In the late s, the worldwide trade in illicit AAS increased significantly, and authorities announced record captures on three continents.
A review published in the Journal of Obesity in 2011 that looked at 12 clinical trials found that Garcinia Cambogia can increase weight loss by about 0. 88 kg, or 2 pounds, on average, over a period of several weeks (13).
Their conclusion sums it up quite nicely: …Garcinia extractsHCA can cause short-term weight loss. The magnitude of the effect is small, and the clinical relevance is uncertain. I agree.